An experimentally induced osteoarthritis model in horses performed on both metacarpophalangeal and metatarsophalangeal joints: Technical, clinical, imaging, biochemical, macroscopic and microscopic characterization.

Osteoarthritis is a common cause of pain and economic loss in both humans and horses. The horse is recognized as a suitable model for human osteoarthritis, because the thickness, structure, and mechanical properties of equine articular cartilage are highly comparable to those of humans. Although a n...

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Bibliographic Details
Main Authors: Lélia Bertoni, Sandrine Jacquet-Guibon, Thomas Branly, Florence Legendre, Mélanie Desancé, Céline Mespoulhes, Martine Melin, Daniel-Jean Hartmann, Amandine Schmutz, Jean-Marie Denoix, Philippe Galéra, Magali Demoor, Fabrice Audigié
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0235251