Glyceollins trigger anti-proliferative effects through estradiol-dependent and independent pathways in breast cancer cells

Glyceollins trigger anti-proliferative effects through estradiol-dependent and independent pathways in breast cancer cells

Abstract Background Estrogen receptors (ER) α and β are found in both women and men in many tissues, where they have different functions, including having roles in cell proliferation and differentiation of the reproductive tract. In addition to estradiol (E2), a natural hormone, numerous compounds a...

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Bibliographic Details
Main Authors: Sylvain Lecomte, Frederic Chalmel, François Ferriere, Frederic Percevault, Nicolas Plu, Christian Saligaut, Claire Surel, Marie Lelong, Theo Efstathiou, Farzad Pakdel
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Cell Communication and Signaling
Subjects:
Glyceollins
Estrogen receptors
Cell proliferation
Transcriptomic
Gene expression
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12964-017-0182-1

Internet

http://link.springer.com/article/10.1186/s12964-017-0182-1

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