Coenzyme Q10 supplementation mitigates piroxicam-induced oxidative injury and apoptotic pathways in the stomach, liver, and kidney

Coenzyme Q10 supplementation mitigates piroxicam-induced oxidative injury and apoptotic pathways in the stomach, liver, and kidney

Piroxicam (PM) is an oxicam-NSAID commonly recommended for various pain and associated inflammatory disorders. However, it is reported to have a gastric and hepato-renal toxic effect. Therefore, the current research was planned to investigate the possible mechanisms behind the mitigating action of t...

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Bibliographic Details
Main Authors: Ahmed Abdeen, Afaf Abdelkader, Dina Elgazzar, Mohamed Aboubakr, Omnia A. Abdulah, Khaled Shoghy, Mohamed Abdel-Daim, Hamed A. El-Serehy, Agnieszka Najda, Amany El-Mleeh
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
NSAIDs
Nephrotoxicity
Hepatotoxicity
Gastric ulcer
Oxidative stress
COVID-19
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220308209

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http://www.sciencedirect.com/science/article/pii/S0753332220308209

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