Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial CellsSummary

Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial CellsSummary

Background & Aims: Tight junctions form a barrier to the paracellular passage of luminal antigens. Although most tight junction proteins reside within the apical tight junction complex, claudin-18 localizes mainly to the basolateral membrane where its contribution to paracellular ion transpo...

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Bibliographic Details
Main Authors: Tyler J. Caron, Kathleen E. Scott, Nishita Sinha, Sureshkumar Muthupalani, Mahnoor Baqai, Lay-Hong Ang, Yue Li, Jerrold R. Turner, James G. Fox, Susan J. Hagen
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Claudin-2
Paracellular Permeability
Genomic Profile
Ussing Chambers
RNAseq
Gastric Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X20301685

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http://www.sciencedirect.com/science/article/pii/S2352345X20301685

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