Apparent dependence of protein evolutionary rate on number of interactions is linked to biases in protein–protein interactions data sets

<p>Abstract</p> <p>Background</p> <p>Several studies have suggested that proteins that interact with more partners evolve more slowly. The strength and validity of this association has been called into question. Here we investigate how biases in high-throughput protein–...

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Bibliographic Details
Main Authors: Adami Christoph, Bloom Jesse D
Format: Article
Language:English
Published: BMC 2003-10-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/3/21