Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus.

Interaction between pairs of Staphylococcus aureus replication proteins was detected in an Escherichia coli based two-hybrid analysis. A reverse two-hybrid system was constructed for selection of compounds that hindered interaction between interacting protein pairs. A number of cyclic peptides, from...

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Bibliographic Details
Main Authors: Susanne Kjelstrup, Paula Melo Paulon Hansen, Line E Thomsen, Paul Robert Hansen, Anders Løbner-Olesen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24023733/?tool=EBI