μ-opioid/D2 dopamine receptor pharmacophore containing ligands: Synthesis and pharmacological evaluation

Herein, the synthesis and pharmacological evaluation of 13 novel compounds, designed as potential heterobivalent ligands for μ-opioid receptor (MOR) and dopamine D2 receptors (D2DAR), are reported. The compounds consisted of anilido piperidine and N-aryl piperazine moieties, joined by a variable-len...

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Bibliographic Details
Main Authors: Jevtić Ivana I., Penjišević Jelena Z., Savić-Vujović Katarina R., Srebro Dragana P., Vučković Sonja M., Ivanović Milovan D., Kostić-Rajačić Slađana V.
Format: Article
Language:English
Published: Serbian Chemical Society 2020-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2020/0352-51391900118J.pdf