Role of Rab5 in the formation of macrophage-derived foam cell

Abstract Background Foam cells play a key role in the occurrence and pathogenesis of atherosclerosis. Its formation starts with the ingestion of oxidized low-density lipoprotein (oxLDL). The process is associated with Ras related protein in brain 5 (Rab5) which plays a critical role in regulating en...

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Bibliographic Details
Main Authors: Lokwern Chan, Jin Hong, Junjie Pan, Jian Li, Zhichao Wen, Haiming Shi, Jianping Ding, Xinping Luo
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Lipids in Health and Disease
Subjects:
Rab
Online Access:http://link.springer.com/article/10.1186/s12944-017-0559-6