Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups
More than 150 RNA chemical modifications have been identified to date. Among them, methylation of adenosine at the N-6 position (m<sup>6</sup>A) is crucial for RNA metabolism, stability and other important biological events. In particular, this is the most abundant mark found in mRNA in...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-07-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/14/3241 |