Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa.

Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa.

PURPOSE:To test the efficacy of systemic gene delivery of a mutant form of erythropoietin (EPO-R76E) that has attenuated erythropoietic activity, in a mouse model of autosomal dominant retinitis pigmentosa. METHODS:Ten-day old mice carrying one copy of human rhodopsin with the P23H mutation and both...

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Bibliographic Details
Main Authors: Tonia S Rex, Lorraine Kasmala, Wesley S Bond, Ana M de Lucas Cerrillo, Kristi Wynn, Alfred S Lewin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4907422?pdf=render

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http://europepmc.org/articles/PMC4907422?pdf=render

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