Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergence.
Gene duplication is a major driver of evolutionary divergence. In most vertebrates a single PAX6 gene encodes a transcription factor required for eye, brain, olfactory system, and pancreas development. In zebrafish, following a postulated whole-genome duplication event in an ancestral teleost, dupli...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-02-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2242813?pdf=render |