Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors.

BACKGROUND:Central nervous system (CNS) primitive neuroectodermal tumors (PNETs) are malignant primary brain tumors that occur in young infants. Using current standard therapy, up to 80% of the children still dies from recurrent disease. Cellular immunotherapy might be key to improve overall surviva...

Full description

Bibliographic Details
Main Authors: Jeroen F Vermeulen, Wim van Hecke, Wim G M Spliet, José Villacorta Hidalgo, Paul Fisch, Roel Broekhuizen, Niels Bovenschen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4786147?pdf=render