Tissue-autonomous immune response regulates stress signaling during hypertrophy

Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway via RasV12-overexpression in the postmitotic salivary glands (SGs) of Drosophila larvae, we...

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Bibliographic Details
Main Authors: Robert Krautz, Dilan Khalili, Ulrich Theopold
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
JNK
Online Access:https://elifesciences.org/articles/64919