Docosahexaenoic acid modulates brain-derived neurotrophic factor via GPR40 in the brain and alleviates diabesity-associated learning and memory deficits in mice

GPR40 (Free fatty acid receptor 1) has emerged as an important therapeutic target for diabetes. Several studies have demonstrated the association of comorbid psychiatric conditions with decreased n-3 polyunsaturated fatty acids, which may act as an agonist for GPR40. In this study, we for the first...

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Bibliographic Details
Main Authors: Chandan Sona, Ajeet Kumar, Shalini Dogra, Boda Arun Kumar, Deepmala Umrao, Prem N. Yadav
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Neurobiology of Disease
Subjects:
DHA
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118302080