Enantioselective Separation of Mirtazapine and Its Metabolites by Capillary Electrophoresis with Acetonitrile Field-Amplified Sample Stacking and Its Application

A simple, rapid and sensitive chiral capillary zone electrophoresis coupled with acetonitrile-field-amplified sample stacking method was developed that allows the simultaneous enantioselective separation of the mirtazapine, N-demethylmirtazapine, 8-hydroxymirtazapine and mirtazapine-N-oxide. The sep...

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Bibliographic Details
Main Authors: Jun Wen, Wen-Ting Zhang, Wei-Qun Cao, Ji Li, Fang-Yuan Gao, Nan Yang, Guo-Rong Fan
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/4/4907