FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways.

FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways.

Fibroblast growth factor 19 (FGF19) is a hormone-like protein that regulates carbohydrate, lipid and bile acid metabolism. At supra-physiological doses, FGF19 also increases hepatocyte proliferation and induces hepatocellular carcinogenesis in mice. Much of FGF19 activity is attributed to the activa...

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Bibliographic Details
Main Authors: Ai-Luen Wu, Sally Coulter, Christopher Liddle, Anne Wong, Jeffrey Eastham-Anderson, Dorothy M French, Andrew S Peterson, Junichiro Sonoda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060878?pdf=render

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http://europepmc.org/articles/PMC3060878?pdf=render

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