Virus-derived DNA drives mosquito vector tolerance to arboviral infection

Mosquitoes tolerate long-lasting viral infections, which makes them efficient vectors for human viral diseases. Here, the authors show that the tolerance of Aedesmosquitoes to infection with dengue or chikungunya viruses depends on the production of viral-derived DNA by cellular reverse transcriptas...

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Bibliographic Details
Main Authors: Bertsy Goic, Kenneth A. Stapleford, Lionel Frangeul, Aurélien J. Doucet, Valérie Gausson, Hervé Blanc, Nidia Schemmel-Jofre, Gael Cristofari, Louis Lambrechts, Marco Vignuzzi, Maria-Carla Saleh
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12410