Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients

Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients

Abstract Key elements for viral pathogenesis include viral strains, viral load, co-infection, and host responses. Several studies analyzing these factors in the function of disease severity of have been published; however, no studies have shown how all of these factors interplay within a defined coh...

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Bibliographic Details
Main Authors: Eric C. Rouchka, Julia H. Chariker, Brian Alejandro, Robert S. Adcock, Richa Singhal, Julio Ramirez, Kenneth E. Palmer, Amanda B. Lasnik, Ruth Carrico, Forest W. Arnold, Stephen Furmanek, Mei Zhang, Leslie A. Wolf, Sabine Waigel, Wolfgang Zacharias, Jose Bordon, Donghoon Chung
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95197-y

Internet

https://doi.org/10.1038/s41598-021-95197-y

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