Perinatal asphyxia reduces dentate granule cells and exacerbates methamphetamine-induced hyperlocomotion in adulthood.

Perinatal asphyxia reduces dentate granule cells and exacerbates methamphetamine-induced hyperlocomotion in adulthood.

BACKGROUND: Obstetric complications have been regarded as a risk factor for schizophrenia later in life. One of the mechanisms underlying the association is postulated to be a hypoxic process in the brain in the offspring around the time of birth. Hippocampus is one of the brain regions implicated i...

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Main Authors: Tomoyasu Wakuda, Hideo Matsuzaki, Katsuaki Suzuki, Yasuhide Iwata, Chie Shinmura, Shiro Suda, Keiko Iwata, Shigeyuki Yamamoto, Genichi Sugihara, Kenji J Tsuchiya, Takatoshi Ueki, Kazuhiko Nakamura, Daiichiro Nakahara, Nori Takei, Norio Mori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2572851?pdf=render

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http://europepmc.org/articles/PMC2572851?pdf=render

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