Mechanisms of antidiarrhoeal effects by diosmectite in human intestinal cells

Mechanisms of antidiarrhoeal effects by diosmectite in human intestinal cells

Abstract Background Rotavirus (RV) induces diarrhoea through a sequence of enterotoxic and cytotoxic effects. The former are NSP4-dependent, induce calcium-dependent chloride secretion and involve oxidative stress. Diosmectite (DS) is a natural clay that has been recommended as an active therapy for...

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Bibliographic Details
Main Authors: Vittoria Buccigrossi, Carla Russo, Amedeo Guarino, Maiara Brusco de Freitas, Alfredo Guarino
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Gut Pathogens
Subjects:
Rotavirus infection
Diosmectite
Oxidative stress
Chloride secretion
Online Access:http://link.springer.com/article/10.1186/s13099-017-0172-2

Internet

http://link.springer.com/article/10.1186/s13099-017-0172-2

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