High-coverage targeted lipidomics revealed dramatic lipid compositional changes in asthenozoospermic spermatozoa and inverse correlation of ganglioside GM3 with sperm motility

Abstract Background It has been previously demonstrated that cholesterol content and cholesterol/phospholipid ratio were significantly higher in asthenozoospermia and oligoasthenoteratozoospermia. The majority of published studies have investigated the fatty acid composition of phospholipids rather...

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Bibliographic Details
Main Authors: Shuqiang Chen, Ming Wang, Li Li, Jun Wang, Xuhui Ma, Hengde Zhang, Yang Cai, Bin Kang, Jianlei Huang, Bo Li
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Reproductive Biology and Endocrinology
Subjects:
GM3
Online Access:https://doi.org/10.1186/s12958-021-00792-3