Stochastic theory of early viral infection: continuous versus burst production of virions.

Viral production from infected cells can occur continuously or in a burst that generally kills the cell. For HIV infection, both modes of production have been suggested. Standard viral dynamic models formulated as sets of ordinary differential equations can not distinguish between these two modes of...

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Bibliographic Details
Main Authors: John E Pearson, Paul Krapivsky, Alan S Perelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3033366?pdf=render