Automated TruTip nucleic acid extraction and purification from raw sputum.

Automated nucleic acid extraction from primary (raw) sputum continues to be a significant technical challenge for molecular diagnostics. In this work, we developed a prototype open-architecture, automated nucleic acid workstation that includes a mechanical homogenization and lysis function integrate...

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Bibliographic Details
Main Authors: Nitu Thakore, Ryan Norville, Molly Franke, Roger Calderon, Leonid Lecca, Michael Villanueva, Megan B Murray, Christopher G Cooney, Darrell P Chandler, Rebecca C Holmberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6033430?pdf=render