Derivation of multivariate syndromic outcome metrics for consistent testing across multiple models of cervical spinal cord injury in rats.

Spinal cord injury (SCI) and other neurological disorders involve complex biological and functional changes. Well-characterized preclinical models provide a powerful tool for understanding mechanisms of disease; however managing information produced by experimental models represents a significant ch...

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Bibliographic Details
Main Authors: Adam R Ferguson, Karen-Amanda Irvine, John C Gensel, Jessica L Nielson, Amity Lin, Johnathan Ly, Mark R Segal, Rajiv R Ratan, Jacqueline C Bresnahan, Michael S Beattie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3609747?pdf=render