Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period

Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period

Aim: Characterizing the response to myocardial infarction (MI) in the regenerative sheep fetus heart compared to the post-natal non-regenerative adolescent heart may reveal key morphological and molecular differences that equate to the response to MI in humans. We hypothesized that the immediate res...

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Bibliographic Details
Main Authors: Mitchell C. Lock, Jack R. T. Darby, Jia Yin Soo, Doug A. Brooks, Sunthara Rajan Perumal, Joseph B. Selvanayagam, Mike Seed, Christopher K. Macgowan, Enzo R. Porrello, Ross L. Tellam, Janna L. Morrison
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Physiology
Subjects:
cardiac
fetus
myocardial infarction
proliferation
repair
sheep
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00208/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00208/full

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