The insulin-like growth factor system in chronic kidney disease: Pathophysiology and therapeutic opportunities

The growth hormone–insulin-like growth factor–insulin-like growth factor binding protein (GH–IGF–IGFBP) axis plays a critical role in the maintenance of normal renal function and the pathogenesis and progression of chronic kidney disease (CKD). Serum IGF-I and IGFBPs are altered with different stage...

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Bibliographic Details
Main Author: Youngman Oh
Format: Article
Language:English
Published: The Korean Society of Nephrology 2012-03-01
Series:Kidney Research and Clinical Practice
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211913211000064