Counteraction of the multifunctional restriction factor tetherin

The interferon-inducible restriction factor tetherin (also known as CD317, BST-2 or HM1.24) has emerged as a key component of the antiviral immune response. Initially, tetherin was shown to restrict replication of various enveloped viruses by inhibiting the release of budding virions from infected c...

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Bibliographic Details
Main Author: Daniel eSauter
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Microbiology
Subjects:
HIV
Nef
Vpu
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00163/full