miR-452 Reverses Abnormal Glycosylation Modification of ERα and Estrogen Resistance in TNBC (Triple-Negative Breast Cancer) Through Targeting UGT1A1

miR-452 Reverses Abnormal Glycosylation Modification of ERα and Estrogen Resistance in TNBC (Triple-Negative Breast Cancer) Through Targeting UGT1A1

Background: The breast epithelial cells in patients with triple-negative breast cancer (TNBC) actually have specific estrogen receptor (ER) expression, and the abnormal glycosylation of UGT1A1 in TNBC cells resulted in abnormal expression and function of ERα through regulating the modification of ER...

Full description

Bibliographic Details
Main Authors: Yan Li, Yidong Zhou, Feng Mao, Songjie Shen, Bin Zhao, Yali Xu, Yan Lin, Xiaohui Zhang, Xi Cao, Ying Xu, Chang Chen, Jinqian Zhang, Qiang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
triple-negative breast cancer (TNBC)
estrogen receptor (ER)
uridine diphosphate glucuronyl transferase (UDPGT
UGT)
glycosylation modification
estrogen resistance
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01509/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01509/full

Similar Items