The glutathione synthesis gene Gclm modulates amphiphilic polymer-coated CdSe/ZnS quantum dot-induced lung inflammation in mice.

Quantum dots (QDs) are unique semi-conductor fluorescent nanoparticles with potential uses in a variety of biomedical applications. However, concerns exist regarding their potential toxicity, specifically their capacity to induce oxidative stress and inflammation. In this study we synthesized CdSe/Z...

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Bibliographic Details
Main Authors: Lisa A McConnachie, Dianne Botta, Collin C White, Chad S Weldy, Hui-Wen Wilkerson, Jianbo Yu, Russell Dills, Xiaozhong Yu, William C Griffith, Elaine M Faustman, Federico M Farin, Sean E Gill, William C Parks, Xiaoge Hu, Xiaohu Gao, David L Eaton, Terrance J Kavanagh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3664581?pdf=render