Inhibition of Tumor Growth by Dietary Indole-3-Carbinol in a Prostate Cancer Xenograft Model May Be Associated with Disrupted Gut Microbial Interactions

Inhibition of Tumor Growth by Dietary Indole-3-Carbinol in a Prostate Cancer Xenograft Model May Be Associated with Disrupted Gut Microbial Interactions

Accumulated evidence suggests that the cruciferous vegetables-derived compound indole-3-carbinol (I3C) may protect against prostate cancer, but the precise mechanisms underlying its action remain unclear. This study aimed to verify the hypothesis that the beneficial effect of dietary I3C may be due...

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Bibliographic Details
Main Authors: Yanbei Wu, Robert W. Li, Haiqiu Huang, Arnetta Fletcher, Lu Yu, Quynhchi Pham, Liangli Yu, Qiang He, Thomas T. Y. Wang
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Nutrients
Subjects:
indole-3-carbinol
prostate cancer
gut microbiota
microbial interactions
co-occurrence network
Online Access:https://www.mdpi.com/2072-6643/11/2/467

Internet

https://www.mdpi.com/2072-6643/11/2/467

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