The influence of oleic acid-propylene glycol mixture and iontophoresis to propranolol transdermal transport

Propranolol has an intensive first pass metabolism, resulted in a low oral bioavailability. One alternative to circumvent such problem is the delivery by transdermal route. The objective of this study was to evaluate the effect of oleic acid 10 % (in propylene glycol 20 %) as enhancer, with and with...

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Bibliographic Details
Main Authors: Lucia Hendriati, Akhmad Kharis Nugroho
Format: Article
Language:English
Published: Universitas Gadjah Mada 2009-12-01
Series:Indonesian Journal of Pharmacy
Subjects:
Online Access:http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/531