Transcriptional activation of the adenoviral genome is mediated by capsid protein VI.

Gene expression of DNA viruses requires nuclear import of the viral genome. Human Adenoviruses (Ads), like most DNA viruses, encode factors within early transcription units promoting their own gene expression and counteracting cellular antiviral defense mechanisms. The cellular transcriptional repre...

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Bibliographic Details
Main Authors: Sabrina Schreiner, Ruben Martinez, Peter Groitl, Fabienne Rayne, Remi Vaillant, Peter Wimmer, Guillaume Bossis, Thomas Sternsdorf, Lisa Marcinowski, Zsolt Ruzsics, Thomas Dobner, Harald Wodrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22427750/pdf/?tool=EBI