Flow-cytometric assessment of cellular poly(ADP-ribosyl)ation capacity in peripheral blood lymphocytes
<p>Abstract</p> <p>Background</p> <p>Poly(ADP-ribosyl)ation is a posttranslational modification of nuclear proteins catalysed by poly(ADP-ribose) polymerases (PARPs), using NAD<sup>+ </sup>as a substrate. Activation of PARP-1 is in immediate response to DNA...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-07-01
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| Series: | Immunity & Ageing |
| Online Access: | http://www.immunityageing.com/content/3/1/8 |