Durable response to programmed death-1 (PD-1) blockade in a metastatic gastric cancer patient with mismatch repair deficiency and microsatellite instability

Mismatch repair deficiency (dMMR) or microsatellite instability (MSI) has been reported as a predictive biomarker for responses to programmed death-1 (PD-1) blockade in metastatic colorectal cancer. A high response rate to anti-PD-1 therapy was observed in other cancer types with MSI. We report a ch...

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Bibliographic Details
Main Authors: Ting-Hui Wu, Emily Han-Chung Hsiue, Chang-Tsu Yuan, Li-Hui Tseng, Chia-Chi Lin, Kun-Huei Yeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-06-01
Series:Journal of Cancer Research and Practice
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2311300616301525