Deiodinase knockdown during early zebrafish development affects growth, development, energy metabolism, motility and phototransduction.

Deiodinase knockdown during early zebrafish development affects growth, development, energy metabolism, motility and phototransduction.

Thyroid hormone (TH) balance is essential for vertebrate development. Deiodinase type 1 (D1) and type 2 (D2) increase and deiodinase type 3 (D3) decreases local intracellular levels of T3, the most important active TH. The role of deiodinase-mediated TH effects in early vertebrate development is onl...

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Bibliographic Details
Main Authors: Enise Bagci, Marjolein Heijlen, Lucia Vergauwen, An Hagenaars, Anne M Houbrechts, Camila V Esguerra, Ronny Blust, Veerle M Darras, Dries Knapen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4391947?pdf=render

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http://europepmc.org/articles/PMC4391947?pdf=render

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