Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats

Early life stress (ELS) is a risk factor for developing functional gastrointestinal disorders, and has been proposed to be related to a central amplification of sensory input and resultant visceral hyperalgesia. We sought to characterize ELS-related changes in functional brain responses during acute...

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Bibliographic Details
Main Authors: D.P. Holschneider, Y. Guo, E.A. Mayer, Z. Wang
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Neurobiology of Stress
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289515300229