Human β-defensin-2 production upon viral and bacterial co-infection is attenuated in COPD.

Human β-defensin-2 production upon viral and bacterial co-infection is attenuated in COPD.

Viral-bacterial co-infections are associated with severe exacerbations of COPD. Epithelial antimicrobial peptides, including human β-defensin-2 (HBD-2), are integral to innate host defenses. In this study, we examined how co-infection of airway epithelial cells with rhinovirus and Pseudomonas aerugi...

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Bibliographic Details
Main Authors: Jason W Arnason, James C Murphy, Cora Kooi, Shahina Wiehler, Suzanne L Traves, Christopher Shelfoon, Barbara Maciejewski, Curtis J Dumonceaux, W Shawn Lewenza, David Proud, Richard Leigh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5425185?pdf=render

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http://europepmc.org/articles/PMC5425185?pdf=render

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