Voxel-based MRI intensitometry reveals extent of cerebral white matter pathology in amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is characterized by progressive loss of upper and lower motor neurons. Advanced MRI techniques such as diffusion tensor imaging have shown great potential in capturing a common white matter pathology. However the sensitivity is variable and diffusion tensor imagin...

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Bibliographic Details
Main Authors: Viktor Hartung, Tino Prell, Christian Gaser, Martin R Turner, Florian Tietz, Benjamin Ilse, Martin Bokemeyer, Otto W Witte, Julian Grosskreutz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25133577/pdf/?tool=EBI