Changes in circulating miRNA19a-3p precede insulin resistance programmed by intra-uterine growth retardation in mice

Changes in circulating miRNA19a-3p precede insulin resistance programmed by intra-uterine growth retardation in mice

Objective: Individuals born with intrauterine growth retardation (IUGR) are more prone to cardio-metabolic diseases as adults, and environmental changes during the perinatal period have been identified as potentially crucial factors. We have studied in a preclinical model early-onset molecular alter...

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Bibliographic Details
Main Authors: Sarah Saget, Rong Cong, Lyvianne Decourtye, Marie-Laure Endale, Laetitia Martinerie, Clémence Girardet, Claire Perret, Maud Clemessy, Patricia Leneuve, Laetitia Dinard, Badreddine Mohand Oumoussa, Dominique Farabos, Antonin Lamazière, Marc Lombès, Marthe Moldes, Bruno Fève, David Tregouet, Yves Le Bouc, Laurent Kappeler
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Metabolism
Subjects:
Nutrition
microRNA19a
Histone modifications
Epigenetics
Biomarker
DOHaD
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301575

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http://www.sciencedirect.com/science/article/pii/S2212877820301575

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