Pathway analysis of genetic factors associated with spontaneous preterm birth and pre-labor preterm rupture of membranes.

Pre-term birth (PTB) remains the leading cause of infant mortality and morbidity. Its etiology is multifactorial, with a strong genetic component. Genetic predisposition for the two subtypes, spontaneous PTB with intact membranes (sPTB) and preterm prelabor rapture of membranes (PPROM), and differen...

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Bibliographic Details
Main Authors: Antonio Capece, Olga Vasieva, Shireen Meher, Zarko Alfirevic, Ana Alfirevic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4181300?pdf=render