Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration

Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration

During gastrulation, neural crest cells are specified at the neural plate border, as characterized by Pax7 expression. Using single-cell RNA sequencing coupled with high-resolution in situ hybridization to identify novel transcriptional regulators, we show that chromatin remodeler Hmga1 is highly ex...

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Bibliographic Details
Main Authors: Shashank Gandhi, Erica J Hutchins, Krystyna Maruszko, Jong H Park, Matthew Thomson, Marianne E Bronner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
neural crest
chromatin remodeler
Wnt signaling
specification
cell migration
Online Access:https://elifesciences.org/articles/57779

Internet

https://elifesciences.org/articles/57779

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