Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration
During gastrulation, neural crest cells are specified at the neural plate border, as characterized by Pax7 expression. Using single-cell RNA sequencing coupled with high-resolution in situ hybridization to identify novel transcriptional regulators, we show that chromatin remodeler Hmga1 is highly ex...
Main Authors: | Shashank Gandhi, Erica J Hutchins, Krystyna Maruszko, Jong H Park, Matthew Thomson, Marianne E Bronner |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-09-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/57779 |
Similar Items
-
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis
by: Yu Ji, et al.
Published: (2019-09-01) -
Transcriptomic Identification of Draxin-Responsive Targets During Cranial Neural Crest EMT
by: Erica J. Hutchins, et al.
Published: (2021-02-01) -
Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner
by: Arun Devotta, et al.
Published: (2018-07-01) -
Wnt4 and Wnt6 secreted growth and differentiation factors and neural crest in the control of kidney development
by: Itäranta, P. (Petri)
Published: (2007) -
Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis
by: Debadrita Bhattacharya, et al.
Published: (2018-12-01)