Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues

Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues

Abstract Background Delivery of stem cells to the failing heart is a promising therapeutic strategy. However, the improvement in cardiac function in animal studies has not fully translated to humans. To help bridge the gap between species, we investigated the effects of adult human cardiac stem cell...

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Bibliographic Details
Main Authors: Jack F. Murphy, Joshua Mayourian, Francesca Stillitano, Sadek Munawar, Kathleen M. Broughton, Esperanza Agullo-Pascual, Mark A. Sussman, Roger J. Hajjar, Kevin D. Costa, Irene C. Turnbull
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Stem Cell Research & Therapy
Subjects:
Human cardiac stem cells
Human engineered cardiac tissue
Contractility
Myocardial function
Cardiomyocyte maturation
Online Access:https://doi.org/10.1186/s13287-019-1486-4

Internet

https://doi.org/10.1186/s13287-019-1486-4

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