Rrp12 and the Exportin Crm1 participate in late assembly events in the nucleolus during 40S ribosomal subunit biogenesis.

During the biogenesis of small ribosomal subunits in eukaryotes, the pre-40S particles formed in the nucleolus are rapidly transported to the cytoplasm. The mechanisms underlying the nuclear export of these particles and its coordination with other biogenesis steps are mostly unknown. Here we show t...

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Bibliographic Details
Main Authors: Giulia Moriggi, Blanca Nieto, Mercedes Dosil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4256259?pdf=render