Identification of sequence changes in myosin II that adjust muscle contraction velocity.

The speed of muscle contraction is related to body size; muscles in larger species contract at slower rates. Since contraction speed is a property of the myosin isoform expressed in a muscle, we investigated how sequence changes in a range of muscle myosin II isoforms enable this slower rate of musc...

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Bibliographic Details
Main Authors: Chloe A Johnson, Jake E McGreig, Sarah T Jeanfavre, Jonathan Walklate, Carlos D Vera, Marta Farré, Daniel P Mulvihill, Anthony J Baines, Martin Ridout, Leslie A Leinwand, Mark N Wass, Michael A Geeves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001248