Therapeutic Benefit of Treatment of Stroke with Simvastatin and Human Umbilical Cord Blood Cells: Neurogenesis, Synaptic Plasticity, and Axon Growth

The therapeutic efficacy of cell-based therapy after stroke can be enhanced by making the host brain tissue more receptive to the administered cells, which thereby facilitates brain plasticity. We hypothesized that simvastatin increases human umbilical cord blood cell (HUCBC) migration into the isch...

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Bibliographic Details
Main Authors: Xu Cui, Michael Chopp, Amjad Shehadah, Alex Zacharek, Nicole Kuzmin-Nichols, Cyndy Davis Sanberg, Junhao Dai, Chunling Zhang, Yuji Ueno, Cynthia Roberts, Jieli Chen
Format: Article
Language:English
Published: SAGE Publishing 2012-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X627417