Predicted impact of mass drug administration on the development of protective immunity against Schistosoma haematobium.

Previous studies suggest that protective immunity against Schistosoma haematobium is primarily stimulated by antigens from dying worms. Praziquantel treatment kills adult worms, boosting antigen exposure and protective antibody levels. Current schistosomiasis control efforts use repeated mass drug a...

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Bibliographic Details
Main Authors: Kate M Mitchell, Francisca Mutapi, Takafira Mduluza, Nicholas Midzi, Nicholas J Savill, Mark E J Woolhouse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4117464?pdf=render