The platelet fibrinogen receptor: from megakaryocyte to the mortuary
Platelets are integral to normal haemostatic function and act to control vascular haemorrhage with the formation of a stable clot. The fibrinogen receptor (glycoprotein IIb/IIIa [GPIIb/IIIa]) is the most abundant platelet integrin and, by binding fibrinogen, facilitates irreversible binding of plate...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-05-01
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Series: | JRSM Cardiovascular Disease |
Online Access: | https://doi.org/10.1258/cvd.2012.012007 |