The platelet fibrinogen receptor: from megakaryocyte to the mortuary

Platelets are integral to normal haemostatic function and act to control vascular haemorrhage with the formation of a stable clot. The fibrinogen receptor (glycoprotein IIb/IIIa [GPIIb/IIIa]) is the most abundant platelet integrin and, by binding fibrinogen, facilitates irreversible binding of plate...

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Bibliographic Details
Main Authors: Ferro Albert, Floyd Christopher N
Format: Article
Language:English
Published: SAGE Publishing 2012-05-01
Series:JRSM Cardiovascular Disease
Online Access:https://doi.org/10.1258/cvd.2012.012007