Dietary proanthocyanidins modulate the rhythm of BMAL1 expression and induce RORα transactivation in HepG2 cells

Proanthocyanidins (PAs), a flavonoid sub-class, alter the expression of clock genes in the liver of lean and obese rats. The present study aimed to determine whether PAs could modulate the 24-hour rhythmicity of clock gene expression and to identify the molecular mechanism through which PAs could ad...

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Bibliographic Details
Main Authors: Aleix Ribas-Latre, Josep M. Del Bas, Laura Baselga-Escudero, Ester Casanova, Anna Arola-Arnal, M. Josepa Salvadó, Cinta Bladé, Lluis Arola
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615000213