Dietary proanthocyanidins modulate the rhythm of BMAL1 expression and induce RORα transactivation in HepG2 cells
Proanthocyanidins (PAs), a flavonoid sub-class, alter the expression of clock genes in the liver of lean and obese rats. The present study aimed to determine whether PAs could modulate the 24-hour rhythmicity of clock gene expression and to identify the molecular mechanism through which PAs could ad...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-03-01
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Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464615000213 |